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Ketogenic Diet As Adjunctive Therapy For Cancer

Introduction The ketogenic diet has been established as a safe and effective treatment modality for epilepsy, and evidence is emerging revealing its potential as treatment for various other diseases, neurological and otherwise. Interest in cancer as a metabolic disease is being renewed, with tumour metabolism being investigated as a possible target for cancer therapies, especially […]

A Systematic Review of the Use of the Ketogenic Diet in Childhood Epilepsy


The ketogenic diet has been used in the treatment of intractable childhood epilepsy since the 1920s. A systematic review of the efficacy, adverse reactions, and costs associated with using the diet was performed. PubMed and Ovid searches were performed using the keywords epilepsy/therapy, dietary therapy, ketogenic diet, adverse events, and costs. Download

The Ketogenic Diet: One Decade Later

The ketogenic diet, a high fat, adequate protein, low carbohydrate diet, has, during the past decade, had a resurgence of interest for the treatment of difficult-tocontrol seizures in children. This review traces its history, reviews its uses and side effects, and discusses possible alternatives and the diet’s possible mechanisms of action. Finally, this review looks […]

Low glycemic index diet in children and young adults with refractory epilepsy: First Italian experience

This is the report on the first Italian experience with the low glycemic index diet (LGIT) in a group of children, adolescents and young adults with refractory epileptic encephalopathies. A retrospective chart review was performed on patients initiating the LGIT in an outpatient setting from 2005 to 2010. Demographic and clinical information including seizure type, […]

Fasting versus Gradual Initiation of the Ketogenic Diet: A Prospective, Randomized Clinical Trial of Efficacy

Summary: Purpose: The ketogenic diet (KD) is a 90% fat diet of the KD requires hospital admission because of the complexity of the protocol and frequent mild and moderate adverse events. The purpose of the study was to compare the efficacy of a gradual KD initiation with the standard KD initiation preceded by a 24- […]

Should we routinely use modified Atkins diet instead of regular ketogenic diet to treat children with epilepsy?

The modified Atkins diet (MAD) consists of a nearly balanced diet without any age-dependent restriction of recommended daily calorie intake. Recently, there has been a marked increase in the use of the MAD in the treatment of epilepsy. Over the last 8 years, evidence suggesting that the MAD may exhibit similar anticonvulsant properties as the […]